The Patient Monitoring System (PMS) is a monitoring system, it is used for monitoring signals including Electrocardiograph (ECG), Invasive and Non-Invasive Blood Pressure, Oxygen Saturation in Human Blood (SpO2), Body Temperature and other Gases etc. In PMS, the multiple sensors and is used for receiving signals like as ECG, SpO2Finger Sensor, Blood Pressure Cuff and Temperature Probe to measure the signals. The system consists of a pulse rate monitoring software and a wearable device that can measure a subject's temperature and pulse rate only by using a fingertip. The device is able to record the measurement data and interface to PC via Arduino microcontroller.